{"id":25,"url":"https://cclm.media-doc.io/conditions/25/","name":"Corneal Microcysts and Vacuoles","category":"Cornea","detail":"<h2>Symptoms</h2>\n\n<ul>\n\t<li>Generally none</li>\n\t<li>May be mild irritation or hazing of vision</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Microcysts show reversed illumination in marginal retro illumination (higher refractive index of necrotic cells)</li>\n\t<li>Vacuoles show non-reversed illumination and are larger and more rounded</li>\n\t<li>Punctate staining may be seen</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Microcysts are incompletely formed cells which move through the epithelium with normal cellular turnover</li>\n\t<li>Due to chronic hypoxia. Typically take several months to occur</li>\n\t<li>Can also be seen in non-CL wearers</li>\n\t<li>Small numbers of microcysts in a CL wearer is considered normal</li>\n\t<li>Vacuoles are fluid filled spaces due to chronic hypoxia</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Occasional</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/11\">Microcystic Edema (epithelial edema)</a></li>\n\t<li><a href=\"/condition/66\">See: Infiltrates and Opacities &ndash; Differential Diagnosis</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Change to high Dk/t lenses, reduce the number of nights wear/week if EW, or change to DW or DD</li>\n\t<li>May be a temporary increase in microcyst numbers after ceasing EW or changing from low Dk to high Dk EW lens</li>\n</ul>","images":[{"name":"Corneal Microcysts and Vacuoles","file":"https://cclm-static.s3.amazonaws.com/images/microcysts-vacuoles_zoom.jpg"}],"type":1,"videos":[],"wear":false,"ceaseWear":false,"changeLens":true,"changeSolutions":false,"changeCare":false,"counseling":false,"dd":false,"dw":true,"gp":false,"replace":false,"review":true,"rewettingDrops":false,"rx":false,"SiHy":true,"toric":false,"tags":[]}