{"id":31,"url":"https://cclm.media-doc.io/conditions/31/","name":"Lens Solution Toxicity","category":"Cornea","detail":"<h2>Symptoms</h2>\n\n<ul>\n\t<li>Stinging or burning on lens insertion</li>\n\t<li>Visual symptoms if severe</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Localized disruption of the corneal epithelial surface (superficial punctate keratitis) &ndash; often marked</li>\n\t<li>Absence of corneal infiltrates</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Effects are generally related to concentration and dosage of chemical preservative(s)</li>\n\t<li>Toxic effects of solution components potentially include hydrogen peroxide (inadequate neutralization), thimerosal, benzalkonium chloride, chlorhexidine</li>\n\t<li>Rare with modern, higher molecular weight preservatives such as polyhexamethylenebiguanide (PHMB) and Polyquaternium</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Uncommon with current multipurpose solutions. Will occur more frequently with inadequate hydrogen peroxide neutralization</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/33\">Solution-induced corneal staining</a></li>\n\t<li><a href=\"/condition/30\">Solution sensitivity</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Counsel on need to neutralize hydrogen peroxide</li>\n\t<li>Rinse lenses with saline prior to insertion</li>\n\t<li>Consider minimal maintenance options including DD lenses</li>\n</ul>","images":[{"name":"Lens Solution Toxicity","file":"https://cclm-static.s3.amazonaws.com/images/solution-toxicity_zoom.jpg"}],"type":1,"videos":[],"wear":false,"ceaseWear":false,"changeLens":false,"changeSolutions":false,"changeCare":true,"counseling":true,"dd":true,"dw":false,"gp":false,"replace":false,"review":true,"rewettingDrops":false,"rx":false,"SiHy":false,"toric":false,"tags":[]}