{"id":33,"url":"https://cclm.media-doc.io/conditions/33/","name":"SICS (solution induced corneal staining)","category":"Cornea","detail":"<p>Solution induced corneal staining (diffuse and annular)</p>\n\n<h2>Symptoms</h2>\n\n<ul>\n\t<li>Frequently asymptomatic</li>\n\t<li>Mild stinging or burning may be experienced on lens insertion and immediately following lens removal</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Maximal staining often occurs after 2 hours of lens wear</li>\n\t<li>Superficial punctate keratitis, often in an annular pattern</li>\n\t<li>Superficial punctate keratitis may affect the entire corneal surface</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Research is ongoing with respect to the cause of SICS</li>\n\t<li>The staining may be indicative of cellular compromise</li>\n\t<li>Some theories suggest that SICS illustrates the binding of fluorescein to epithelial cells, with the contact lens preservative molecule acting as a binding agent</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Common, particularly with FDA group II hydrogels (especially those containing NVP) and SiHy materials when used with preserved care systems</li>\n\t<li>Negligible with hydrogen peroxide and not present with daily disposables</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/30\">Solution sensitivity</a></li>\n\t<li><a href=\"/condition/31\">Solution toxicity</a></li>\n\t<li><a href=\"/condition/69\">Contact lens dryness</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Use solutions without added preservatives e.g. Hydrogen peroxide</li>\n\t<li>Rinse lenses with saline prior to insertion; rubbing lenses with the preserved care product prior to storage may also reduce the level of SICS</li>\n\t<li>Select SiHy and disinfection solution combinations known to cause less solution-related corneal staining</li>\n\t<li>Switch to DD lenses</li>\n\t<li>NOTE: If asymptomatic and mild, treatment may not be necessary.</li>\n</ul>","images":[{"name":"SICS (solution induced corneal staining)","file":"https://cclm-static.s3.amazonaws.com/images/sics-diffuse_zoom.jpg"},{"name":"SICS (solution induced corneal staining)","file":"https://cclm-static.s3.amazonaws.com/images/sics-annular_zoom.jpg"}],"type":1,"videos":[{"name":"SICS - Diffuse","videoSrc":"248362240"},{"name":"SICS With/Without a Barrier Filter","videoSrc":"255933001"},{"name":"SICS - Annular","videoSrc":"264431756"}],"wear":false,"ceaseWear":false,"changeLens":true,"changeSolutions":false,"changeCare":true,"counseling":true,"dd":true,"dw":false,"gp":false,"replace":false,"review":true,"rewettingDrops":false,"rx":false,"SiHy":false,"toric":false,"tags":[]}