{"id":4,"url":"https://cclm.media-doc.io/conditions/4/","name":"Blebs (Endothelial)","category":"Cornea","detail":"<p>Endothelial edema</p>\n\n<h2>Symptoms</h2>\n\n<ul>\n\t<li>None</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Black spots which appear to be &ldquo;holes&rdquo; on endothelium when viewed with specular reflection</li>\n\t<li>Intracellular edema of endothelial cells</li>\n\t<li>Maximum response occurs 10-20 minutes after lens insertion.</li>\n\t<li>Reduction in response occurs over initial weeks of lens wear.</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Local decrease in pH, associated with hypoxia and carbon dioxide build-up</li>\n\t<li>Typically occurs in unadapted wearers. Degree related to oxygen transmissibility of the lens material</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Occasional</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/62/\">Guttata</a></li>\n\t<li>See: <a href=\"/condition/62/\">Endothelial Changes &ndash; Differential Diagnosis</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>No action required</li>\n\t<li>May consider refit into SiHy or high Dk GP lenses if response is severe</li>\n</ul>","images":[{"name":"Blebs (Endothelial)","file":"https://cclm-static.s3.amazonaws.com/images/endothelial-bleb_zoom.jpg"}],"type":1,"videos":[],"wear":false,"ceaseWear":false,"changeLens":true,"changeSolutions":false,"changeCare":false,"counseling":false,"dd":false,"dw":false,"gp":false,"replace":false,"review":false,"rewettingDrops":false,"rx":false,"SiHy":true,"toric":false,"tags":[]}