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{
    "id": 20,
    "url": "https://cclm.media-doc.io/conditions/20/?format=api",
    "name": "Infiltrates – Infiltrative Keratitis",
    "category": "Cornea",
    "detail": "<p>Marginal keratitis, asymptomatic infiltrative keratitis, marginal infiltrate, sterile infiltration</p>\n\n<h2>Symptoms</h2>\n\n<ul>\n\t<li>Minor infiltrates may be asymptomatic</li>\n\t<li>Discomfort, foreign body sensation</li>\n\t<li>Redness</li>\n\t<li>Mild photophobia</li>\n\t<li>Symptoms reduce on lens removal</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Single or multiple circular infiltrates in epithelium or anterior stroma</li>\n\t<li>May be unilateral or bilateral</li>\n\t<li>Localized bulbar and/or limbal hyperemia adjacent to infiltrates</li>\n\t<li>Overlying epithelium generally does not stain</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Inflammatory reaction resulting in accumulation of white blood cells in cornea</li>\n\t<li>Response to hypoxia, chemical toxicity, cellular debris, allergens, denatured protein, exotoxins and/or endotoxins from bacteria</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Infrequent</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/24\">Microbial keratitis</a></li>\n\t<li>Adenoviral infection</li>\n\t<li><a href=\"/condition/6\">CLPU</a></li>\n\t<li><a href=\"/condition/66\">See: Infiltrates and Opacities &ndash; Differential Diagnosis</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Remove cause of inflammatory response</li>\n\t<li>In severe cases, discontinue lens wear until infiltrate totally resolves</li>\n\t<li>Prophylactic antibiotic may be prescribed</li>\n\t<li>Mild steroid may be prescribed</li>\n\t<li>Treat blepharitis if present</li>\n\t<li>Review within 1 week. Resolution may require &gt; 2 weeks</li>\n\t<li>May change to DW, change to a higher Dk lens, increase lens replacement frequency (DD), change care system</li>\n</ul>",
    "images": [
        {
            "name": "Infiltrates – Infiltrative Keratitis",
            "file": "https://cclm-static.s3.amazonaws.com/images/infiltrates-keratitis_zoom.jpg"
        }
    ],
    "type": 1,
    "videos": [
        {
            "name": "Infiltrates (Central and Fine)",
            "videoSrc": "248362050"
        },
        {
            "name": "Infiltrates (Diffuse and Peripheral)",
            "videoSrc": "255934350"
        }
    ],
    "wear": false,
    "ceaseWear": true,
    "changeLens": true,
    "changeSolutions": false,
    "changeCare": true,
    "counseling": false,
    "dd": false,
    "dw": false,
    "gp": false,
    "replace": false,
    "review": true,
    "rewettingDrops": false,
    "rx": false,
    "SiHy": true,
    "toric": false,
    "tags": []
}