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{
"id": 31,
"url": "https://cclm.media-doc.io/conditions/31/?format=api",
"name": "Lens Solution Toxicity",
"category": "Cornea",
"detail": "<h2>Symptoms</h2>\n\n<ul>\n\t<li>Stinging or burning on lens insertion</li>\n\t<li>Visual symptoms if severe</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Localized disruption of the corneal epithelial surface (superficial punctate keratitis) – often marked</li>\n\t<li>Absence of corneal infiltrates</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Effects are generally related to concentration and dosage of chemical preservative(s)</li>\n\t<li>Toxic effects of solution components potentially include hydrogen peroxide (inadequate neutralization), thimerosal, benzalkonium chloride, chlorhexidine</li>\n\t<li>Rare with modern, higher molecular weight preservatives such as polyhexamethylenebiguanide (PHMB) and Polyquaternium</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Uncommon with current multipurpose solutions. Will occur more frequently with inadequate hydrogen peroxide neutralization</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/33\">Solution-induced corneal staining</a></li>\n\t<li><a href=\"/condition/30\">Solution sensitivity</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Counsel on need to neutralize hydrogen peroxide</li>\n\t<li>Rinse lenses with saline prior to insertion</li>\n\t<li>Consider minimal maintenance options including DD lenses</li>\n</ul>",
"images": [
{
"name": "Lens Solution Toxicity",
"file": "https://cclm-static.s3.amazonaws.com/images/solution-toxicity_zoom.jpg"
}
],
"type": 1,
"videos": [],
"wear": false,
"ceaseWear": false,
"changeLens": false,
"changeSolutions": false,
"changeCare": true,
"counseling": true,
"dd": true,
"dw": false,
"gp": false,
"replace": false,
"review": true,
"rewettingDrops": false,
"rx": false,
"SiHy": false,
"toric": false,
"tags": []
}