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{
    "id": 33,
    "url": "https://cclm.media-doc.io/conditions/33/?format=api",
    "name": "SICS (solution induced corneal staining)",
    "category": "Cornea",
    "detail": "<p>Solution induced corneal staining (diffuse and annular)</p>\n\n<h2>Symptoms</h2>\n\n<ul>\n\t<li>Frequently asymptomatic</li>\n\t<li>Mild stinging or burning may be experienced on lens insertion and immediately following lens removal</li>\n</ul>\n\n<h2>Signs</h2>\n\n<ul>\n\t<li>Maximal staining often occurs after 2 hours of lens wear</li>\n\t<li>Superficial punctate keratitis, often in an annular pattern</li>\n\t<li>Superficial punctate keratitis may affect the entire corneal surface</li>\n</ul>\n\n<h2>Etiology</h2>\n\n<ul>\n\t<li>Research is ongoing with respect to the cause of SICS</li>\n\t<li>The staining may be indicative of cellular compromise</li>\n\t<li>Some theories suggest that SICS illustrates the binding of fluorescein to epithelial cells, with the contact lens preservative molecule acting as a binding agent</li>\n</ul>\n\n<h2>Prevalence</h2>\n\n<ul>\n\t<li>Common, particularly with FDA group II hydrogels (especially those containing NVP) and SiHy materials when used with preserved care systems</li>\n\t<li>Negligible with hydrogen peroxide and not present with daily disposables</li>\n</ul>\n\n<h2>Differential Diagnosis</h2>\n\n<ul>\n\t<li><a href=\"/condition/30\">Solution sensitivity</a></li>\n\t<li><a href=\"/condition/31\">Solution toxicity</a></li>\n\t<li><a href=\"/condition/69\">Contact lens dryness</a></li>\n</ul>\n\n<h2>Management</h2>\n\n<ul>\n\t<li>Use solutions without added preservatives e.g. Hydrogen peroxide</li>\n\t<li>Rinse lenses with saline prior to insertion; rubbing lenses with the preserved care product prior to storage may also reduce the level of SICS</li>\n\t<li>Select SiHy and disinfection solution combinations known to cause less solution-related corneal staining</li>\n\t<li>Switch to DD lenses</li>\n\t<li>NOTE: If asymptomatic and mild, treatment may not be necessary.</li>\n</ul>",
    "images": [
        {
            "name": "SICS (solution induced corneal staining)",
            "file": "https://cclm-static.s3.amazonaws.com/images/sics-diffuse_zoom.jpg"
        },
        {
            "name": "SICS (solution induced corneal staining)",
            "file": "https://cclm-static.s3.amazonaws.com/images/sics-annular_zoom.jpg"
        }
    ],
    "type": 1,
    "videos": [
        {
            "name": "SICS - Diffuse",
            "videoSrc": "248362240"
        },
        {
            "name": "SICS With/Without a Barrier Filter",
            "videoSrc": "255933001"
        },
        {
            "name": "SICS - Annular",
            "videoSrc": "264431756"
        }
    ],
    "wear": false,
    "ceaseWear": false,
    "changeLens": true,
    "changeSolutions": false,
    "changeCare": true,
    "counseling": true,
    "dd": true,
    "dw": false,
    "gp": false,
    "replace": false,
    "review": true,
    "rewettingDrops": false,
    "rx": false,
    "SiHy": false,
    "toric": false,
    "tags": []
}